Inside Sixers-Cavaliers: LeBron's past meets Sixers' present in home opener originally appeared on NBC Sports Philadelphia
The Sixers opened their season against the team that eliminated them from last year’s playoffs.
Their home opener brings another familiar opponent, particularly for the newest member of their starting lineup.
LeBron James will play his first regular-season home game as a Sixer at 7 p.m. Thursday against the franchise he led for 11 seasons and to the 2016 NBA championship.
It is an appealing storyline, but the game offers more than a reunion.
Cleveland swept all four meetings with Philadelphia last season and advanced to the Eastern Conference finals. The Cavaliers retained their four most important players, added a starting wing and will begin their season against a Sixers team coming off a 106-100 road win over the defending champion Knicks.
Here is how the teams stack up.
WHAT LAST SEASON’S SWEEP SHOWED
In the 2025-2026 campaign, the Cavaliers outscored the Sixers in their meetings by an average of 124.3 to 111.0.
Cleveland won, 132-121, behind 46 points from Donovan Mitchell in the first meeting. Mitchell scored 35 in a 133-107 victory in Philadelphia on Jan. 14.
Two nights later, Jaylon Tyson produced a career-high 39 points as the Cavaliers edged the Sixers, 117-115. Cleveland completed the sweep with a 115-101 win on March 9, when James Harden led the team with 21 points.
The four different leading scorers illustrated Cleveland’s range of options.
Mitchell could take over as a scorer. Tyson capitalized when Philadelphia devoted additional attention to the stars. Harden controlled the final matchup after joining Cleveland in February.
Only the last meeting came after the Cavaliers acquired Harden from the Clippers. Thursday will offer the Sixers their first look at a Cleveland team that had an entire offseason and training camp to build around the Harden-Mitchell backcourt.
The Sixers are also considerably different from the team Cleveland swept.
James and Jaylen Brown have replaced Paul George and Kelly Oubre Jr. in the starting lineup. VJ Edgecombe has taken on a significant role, while Kentavious Caldwell-Pope and Anfernee Simons give Nick Nurse experienced alternatives off the bench.
WHAT CHANGED IN CLEVELAND?
The Cavaliers went 52-30 last season and reached the Eastern Conference finals, where the Knicks swept them.
Cleveland brought back its core four. Mitchell signed a four-year extension, Harden returned on a three-year contract, and Evan Mobley and Jarrett Allen remain under contract.
Harden’s first complete season with Cleveland is the most important change.
He joined the Cavaliers at the trade deadline last February and had to learn Kenny Atkinson’s offense during the season. Cleveland can now build its system around Harden, Mitchell, Mobley and Allen from the beginning.
The Cavaliers also acquired 24-year-old wing Peyton Watson in a five-team sign-and-trade with Denver.
Watson averaged career highs of 14.6 points and 4.9 rebounds last season while shooting 41.1 percent from three-point range. The 6-foot-8 forward is expected to fill Cleveland’s opening at small forward and defend many of the opponent’s best wings.
Cleveland also added Mario Hezonja, who is returning to the NBA after six seasons overseas, and drafted guard Meleek Thomas.
The Cavaliers lost several rotation players, including Dean Wade, Max Strus, Dennis Schröder, Keon Ellis and Larry Nance Jr. Their starting lineup remains formidable, but Atkinson will need to establish a new second unit.
LEBRON TALK
Cleveland spent part of the summer pursuing a third stint with James.
After James chose Philadelphia, Atkinson acknowledged that the Cavaliers needed to move quickly to another option.
“There was probably a day of ‘woe is me,’” Atkinson said. “But the day after, we’re just like, ‘How are we pivoting?’”
Watson became the centerpiece of that pivot.
That creates a fascinating possible matchup Thursday. The player Cleveland acquired after James signed with the Sixers could spend stretches defending him.
James has faced the Cavaliers 26 times during his career. His teams have gone 20-6, and he has averaged 26.9 points, 7.0 rebounds and 7.0 assists. Thursday would be his 27th regular-season game against the franchise.
There is also a Philadelphia connection.
James’ final regular-season game in Philadelphia as a Cavalier came on April 6, 2018. He recorded 44 points, 11 rebounds and 11 assists, but the Sixers survived Cleveland’s comeback from 30 points down and won, 132-130.
The 44 points remain James’ career high against the Sixers.
Thursday, he will enter the same building from the opposite locker room.
WHERE THE MATCHUP COULD TURN
The Sixers’ speed should test Cleveland immediately.
Philadelphia scored 24 fast-break points against New York. Tyrese Maxey accounted for 12, including nine following Knicks turnovers.
Cleveland’s starting lineup features two traditional big men in Mobley and Allen. That gives the Cavaliers considerable rim protection and rebounding, but Maxey will want to push the pace before they can establish their half-court defense.
The Sixers forced 14 turnovers Tuesday and converted them into 22 points. Creating similar opportunities would keep them from having to attack Mobley and Allen on every possession.
Cleveland’s backcourt presents the opposite challenge.
Harden can manipulate a defense through pick-and-rolls and draw extra attention before finding Mobley or Allen. Mitchell scored 81 points across his first two games against Philadelphia last season and remains Cleveland’s most dangerous individual scorer.
Brown, Edgecombe and Caldwell-Pope give the Sixers several possible defenders to place on Mitchell. Maxey’s defensive improvement will also be tested when Cleveland involves him in actions featuring Harden.
The matchup in the middle could depend on Allen’s availability.
Allen was listed as questionable Thursday morning with right patellar tendinopathy. If he plays, Cleveland can keep one of Allen or Mobley on the floor for most of the night.
If Allen is unavailable, Mobley could receive more time at center. That would leave the Cavaliers with fewer conventional options against Joel Embiid, especially with Khalifa Diop and Nae’Qwan Tomlin already ruled out.
A FAMILIAR FACE
Wade spent the first seven seasons of his career with Cleveland before signing a four-year contract with the Sixers in July.
His possible Philadelphia debut would come against the only other NBA team he has known.
Wade missed Tuesday’s opener with a left ankle sprain and remained questionable Thursday morning. If he is cleared, his size and shooting would give Nurse another frontcourt option against Mobley and Allen.
The Sixers played James at center for stretches in New York, while Adem Bona and Jabari Walker received brief opportunities behind Embiid. Wade could give Philadelphia another small-ball option who is familiar with Cleveland’s personnel and Atkinson’s system.
His availability carries added importance with Dominick Barlow, Ariel Hukporti and Tacko Fall ruled out.
WHAT CLEVELAND IS SAYING
The Cavaliers are emphasizing the benefit of beginning the season together after adding Harden in the middle of last year.
“Just us having an opportunity to start off together is already exciting,” Harden told reporters Tuesday.
Harden said Cleveland has spent time developing the different possibilities within his pick-and-roll work with Mobley. The Cavaliers can use Mobley as a screener, roller, passer or shooter depending on how Philadelphia defends Harden.
Atkinson has also indicated that Cleveland’s opening rotation could remain unsettled until game time because of the injuries in its frontcourt.
The Cavaliers enter the season with championship expectations after advancing one round farther in each of the past four postseasons. They lost in the first round in 2023, the second round in 2024 and 2025, and the conference finals last season.
Philadelphia will be their first opportunity to show whether that progression can continue.
INJURY REPORT
According to the NBA’s 6:30 a.m. ET injury report:
Sixers
- Dean Wade: Questionable, left ankle sprain
- Dominick Barlow: Out, low-back stress reaction
- Tacko Fall: Out, left quadriceps strain
- Ariel Hukporti: Out, right Achilles tendon rupture
Cavaliers
- Jarrett Allen: Questionable, right patellar tendinopathy
- Khalifa Diop: Out, left knee injury management
- Nae’Qwan Tomlin: Out, low-back stress reaction
WHAT VEGAS THINKS
FanDuel Research listed the Sixers as 2.5-point favorites Thursday morning. The over-under was set at 235.5 points.
The line reflects a competitive matchup while giving Philadelphia a slight edge at home. It could move if Allen or Wade receives a definitive designation.
James’ first return to Cleveland in a Sixers uniform will come Nov. 6.
Thursday is about something else. It is the first look at Philadelphia’s new stars in front of their home crowd and an early comparison with a Cleveland team that had all the answers against the Sixers last season.









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