Ivica Zubac finished with 26 points and 15 rebounds and James Harden added 23 points and 17 assists as the Clippers ended their three-game losing streak.
The Lakers' hopes of pairing Mark Williams with newly acquired star Luka Doncic have fallen through in the wake of the Charlotte center failing his physical.
Warriors superstar Steph Curry made a timely return to form with a dominant performance in Golden State's 132-111 win over the Chicago Bulls on Saturday night at United Center.
Former Laker Anthony Davis had 26 points, 16 rebounds, seven assists and three blocked shots before leaving in the third quarter while Max Christie scored 23.